Working Group: Topics

 

Completed Topics| Topics Under Review | Topics Identified

 

 

Completed Topics

 

Disorder/Effect
Test to be Assessed*
Clinical Scenario
Target Population
Intended Use
Gene expression profile
Women diagnosed with
breast cancer
Treatment and
recurrence risk

Colorectal Cancer (CRC)

UGT1A1

Individuals diagnosed
with CRC
Treatment with irinotecan

Lynch Syndrome/ Hereditary Nonpolyposis Colorectal Cancer (HNPCC)

Mismatch repair gene mutations

Individuals diagnosed with CRC and their family members
Management of individuals and early detection/prevention for family members

Non-psychotic Depression

CYP450

Individuals diagnosed with depression

Treatment with SSRI drugs

Ovarian Cancer

Genomic Tests

 1) General population of women and;
 2) women at increased risk for ovarian cancer
1) and 2) Detection and management
F5, F2
Individuals with family history or clinical suspicion of thrombophilia
Prevention and management

*variants or mutations in the identified gene or genes

 

Page last updated: June 29, 2009
Page last reviewed: December 23, 2008
Content Source: EGAPP Team