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EGAPP logo

Evaluation of Genomic Applications in Practice and Prevention
Working Group
Completed Topics | Topics Under Review | Topics Under Consideration

Completed Topics

Disorder/Effect
Test Assessed*
Clinical Scenario
Target Population
Intended Use
Gene expression profile
Women diagnosed with
breast cancer
Treatment and
recurrence risk

Depression

CYP450

Individuals diagnosed with depression

Treatment with SSRI drugs

Hereditary Nonpolyposis Colorectal Cancer (HNPCC)

Mismatch repair gene mutations

Individuals diagnosed with CRC and their family members

Management of individuals and early detection/prevention for family members

Ovarian Cancer

Genomic Tests

 1) General population of women and;
 2) women at increased risk  for ovarian cancer

1) and 2) Detection and management

*variants or mutations in the identified gene or genes