Working Group: Topics

 

Working Group: Topics

 

 

 

Completed Topics

 

Topic: Genomic Tests for Ovarian Cancer Detection and Management

EGAPP Recommendation: Pending

Summary Article: Pending

Evidence Report: Genomic Tests for Ovarian Cancer Detection and Management, external link Duke University Evidence-based Practice Center

Supplementary Evidence Report: Pending

Other products: Pending

 

Key Questions:

 

  • Question 1: What is the evidence that ovarian cancer genomic tests performed in a typical clinical laboratory actually measure what they are purported to measure?

 

  • Question 2: What is the sensitivity and specificity of genomic tests in detecting ovarian cancer in asymptomatic and symptomatic women, including high-risk women?

 

  • Question 3: What is the evidence that genomic testing to detect ovarian cancer in asymptomatic women, including high-risk women, changes clinical management and leads to improved clinical outcomes?

 

  • Question 4: What is the evidence that genomic testing in women with clinical suspicionof ovarian cancer or with already-diagnosed ovarian cancer changes clinical management and leads to improved health outcomes?

 

  • Question 5: What are the harms of using genomic tests for ovarian cancer prevention and management?

 

  • Question 6: Has direct-to-consumer and direct-to-physician marketing of genomic tests
    for ovarian cancer increased the “appropriate” use of these tests?

 

Why EGAPP Selected this topic for Review:

Key criteria: Critical need for reliable early detection due to high case fatality rate of ovarian cancer.

 

Other Considerations: Collaboration with CDC Division of Cancer Prevention and Control; promotion of new proteomic screening tests when the report was commissioned.

 

Links to organizations are provided solely as a service to our users. These links do not constitute an endorsement of these organizations or their programs by EGAPP, and none should be inferred. EGAPP is not responsible for the content of the individual organization Web pages found at these links.

 

 

Page last updated: May 15, 2013
Page last reviewed: December 23, 2008
Content Source: OPHG Staff