Working Group: Evidence Reports

• PCA3 Testing for the Diagnosis and Management of Prostate Cancer    (PDF 1.88 MB)
  Blue Cross Blue Shield Technical Evaluation Center | April 2013

• Use of genomic panels to determine risk of developing type 2 diabetes in the general population: a targeted evidence-based review 
  CDC/OPHG in collaboration with IPMMS | March 2013

• Systematic review: EGFR-related pharmacogenetic testing (downstream to KRAS) for predicting clinical benefit to cetuximab and panitumumab in metastatic colorectal cancer
  Center for Health Research, Kaiser Permanente Northwest | June 2011

• Use of genomic profiling to assess risk for cardiovascular disease and identify individualized prevention strategies-A targeted evidence-based review.
  CDC/OPHG in collaboration with IPMMS | December 2010

• Outcomes of Genetic Testing in Adults with a History of Venous Thromboembolism
  The Johns Hopkins University Evidence Based Practice Center | June 2009

• Can UGT1A1 Genotyping Reduce Morbidity and Mortality in Patients with Metastatic Colorectal Cancer Treated with Irinotecan?
  CDC, in conjunction with IPMMS and RTI I January 2009

• EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome.
  CDC/OPHG in collaboration with IPMMS | January 2009

• Impact of Gene Expression Profiling Tests on Breast Cancer Outcomes
  The Johns Hopkins University Evidence Based Practice Center | January 2008

• Hereditary Nonpolyposis Colorectal Cancer: Diagnostic Strategies and Their Implications
  Tufts New England Medical Center Evidence Based Practice Center | May 2007

• Testing for Cytochrome P450 Polymorphisms (CYP450) in Adults with Non-Psychotic Depression Prior to Treatment with Selective Serotonin Reuptake Inhibitors (SSRIs)
  Duke University AHRQ Evidence-based Practice Center | January 2007

• Genomic Tests for Ovarian Cancer Detection and Management
  Duke University AHRQ Evidence-based Practice Center | October 2006